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The FGFR1 inhibitor PD173074 induces mesenchymal–epithelial transition through the transcription factor AP-1
BACKGROUND: Epithelial–mesenchymal transition (EMT) is a crucial process in cancer progression that provides cancer cells with the ability to escape from the primary focus, invade stromal tissues and migrate to distant regions. Cell lines that lack E-cadherin show increased tumorigenesis and metasta...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3798957/ https://ncbi.nlm.nih.gov/pubmed/24045665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.550 |
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