Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia–ischemia

Apoptosis-inducing factor (AIF) may contribute to neuronal cell death, and its influence is particularly prominent in the immature brain after hypoxia–ischemia (HI). A brain-specific AIF splice-isoform (AIF2) has recently been discovered, but has not yet been characterized at the genetic level. The...

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Publicado no:Cell Death Dis
Main Authors: Rodriguez, Juan, Zhang, Yaodong, Li, Tao, Xie, Cuicui, Sun, Yanyan, Xu, Yiran, Zhou, Kai, Huo, Kaiming, Wang, Yafeng, Wang, Xiaoyang, Andersson, Daniel, Ståhlberg, Anders, Xing, Qinghe, Mallard, Carina, Hagberg, Henrik, Modjtahedi, Nazanine, Kroemer, Guido, Blomgren, Klas, Zhu, Changlian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315035/
https://ncbi.nlm.nih.gov/pubmed/30584234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1250-1
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