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Sarcomere length–dependent effects on Ca(2+)-troponin regulation in myocardium expressing compliant titin
Cardiac performance is tightly regulated at the cardiomyocyte level by sarcomere length, such that increases in sarcomere length lead to sharply enhanced force generation at the same Ca(2+) concentration. Length-dependent activation of myofilaments involves dynamic and complex interactions between a...
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| Publicado en: | J Gen Physiol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Rockefeller University Press
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6314383/ https://ncbi.nlm.nih.gov/pubmed/30523116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812218 |
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