Sarcomere length–dependent effects on Ca(2+)-troponin regulation in myocardium expressing compliant titin

Cardiac performance is tightly regulated at the cardiomyocyte level by sarcomere length, such that increases in sarcomere length lead to sharply enhanced force generation at the same Ca(2+) concentration. Length-dependent activation of myofilaments involves dynamic and complex interactions between a...

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Detaylı Bibliyografya
Yayımlandı:J Gen Physiol
Asıl Yazarlar: Li, King-Lun, Methawasin, Mei, Tanner, Bertrand C.W., Granzier, Henk L., Solaro, R. John, Dong, Wen-Ji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314383/
https://ncbi.nlm.nih.gov/pubmed/30523116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812218
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