A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model

BACKGROUND: We examined whether metoclopramide (MCP), a modulator of dopamine and serotonin receptors, alleviated colitis and had synergistic effects when coadministered with 5-aminosalicylic acid (5-ASA) in an experimental model of colitis. METHODS: MCP azo-linked to 5-ASA (5-[4-chloro-2-{2-(diethy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Yang, Yejin, Kim, Wooseong, Kim, Dayoon, Jeong, Seongkeun, Yoo, Jin-Wook, Jung, Yunjin
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312693/
https://ncbi.nlm.nih.gov/pubmed/30643389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S185257
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados