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Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response

KEY POINTS: Leptin is a potent respiratory stimulant. A long functional isoform of leptin receptor, LepR(b), was detected in the carotid body (CB), a key peripheral hypoxia sensor. However, the effect of leptin on minute ventilation (V (E)) and the hypoxic ventilatory response (HVR) has not been suf...

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Dades bibliogràfiques
Publicat a:J Physiol
Autors principals: Caballero‐Eraso, Candela, Shin, Mi‐Kyung, Pho, Huy, Kim, Lenise J, Pichard, Luis E., Wu, Zhi‐Juan, Gu, Chenjuan, Berger, Slava, Pham, Luu, Yeung, Ho‐Yee (Bonnie), Shirahata, Machiko, Schwartz, Alan R., Tang, Wan‐Yee (Winnie), Sham, James S. K., Polotsky, Vsevolod Y.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312428/
https://ncbi.nlm.nih.gov/pubmed/30285278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276900
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