Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response

KEY POINTS: Leptin is a potent respiratory stimulant. A long functional isoform of leptin receptor, LepR(b), was detected in the carotid body (CB), a key peripheral hypoxia sensor. However, the effect of leptin on minute ventilation (V (E)) and the hypoxic ventilatory response (HVR) has not been suf...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Caballero‐Eraso, Candela, Shin, Mi‐Kyung, Pho, Huy, Kim, Lenise J, Pichard, Luis E., Wu, Zhi‐Juan, Gu, Chenjuan, Berger, Slava, Pham, Luu, Yeung, Ho‐Yee (Bonnie), Shirahata, Machiko, Schwartz, Alan R., Tang, Wan‐Yee (Winnie), Sham, James S. K., Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Respiratory
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312428/
https://ncbi.nlm.nih.gov/pubmed/30285278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276900
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