Leptin acts in the carotid bodies to increase minute ventilation during wakefulness and sleep and augment the hypoxic ventilatory response

KEY POINTS: Leptin is a potent respiratory stimulant. A long functional isoform of leptin receptor, LepR(b), was detected in the carotid body (CB), a key peripheral hypoxia sensor. However, the effect of leptin on minute ventilation (V (E)) and the hypoxic ventilatory response (HVR) has not been suf...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Caballero‐Eraso, Candela, Shin, Mi‐Kyung, Pho, Huy, Kim, Lenise J, Pichard, Luis E., Wu, Zhi‐Juan, Gu, Chenjuan, Berger, Slava, Pham, Luu, Yeung, Ho‐Yee (Bonnie), Shirahata, Machiko, Schwartz, Alan R., Tang, Wan‐Yee (Winnie), Sham, James S. K., Polotsky, Vsevolod Y.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Respiratory
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312428/
https://ncbi.nlm.nih.gov/pubmed/30285278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276900
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