Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body

RATIONALE: Obesity leads to resistant hypertension and mechanisms are poorly understood, but high plasma levels of leptin have been implicated. Leptin increases blood pressure acting both centrally in the dorsomedial hypothalamus and peripherally. Sites of the peripheral hypertensive effect of lepti...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Shin, Mi-Kyung, Eraso, Candela Caballero, Mu, Yun-Ping, Gu, Chenjuan, Yeung, Bonnie H.Y., Kim, Lenise J, Liu, Xiao-Ru, Wu, Zhi-Juan, Paudel, Omkar, Pichard, Luis E, Shirahata, Machiko, Tang, Wan-Yee, Sham, James S. K., Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842127/
https://ncbi.nlm.nih.gov/pubmed/31545149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315338
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