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Leptin and Leptin Resistance in the Pathogenesis of Obstructive Sleep Apnea: A Possible Link to Oxidative Stress and Cardiovascular Complications

Obesity-related sleep breathing disorders such as obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) cause intermittent hypoxia (IH) during sleep, a powerful trigger of oxidative stress. Obesity also leads to dramatic increases in circulating levels of leptin, a hormone produce...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Berger, Slava, Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841044/
https://ncbi.nlm.nih.gov/pubmed/29675134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5137947
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