In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://ncbi.nlm.nih.gov/pubmed/30596650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203340
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