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In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://ncbi.nlm.nih.gov/pubmed/30596650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203340
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