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In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://ncbi.nlm.nih.gov/pubmed/30596650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203340
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