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In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni

Morbidity and mortality caused by schistosomiasis are serious public health problems in developing countries. Because praziquantel is the only drug in therapeutic use, the risk of drug resistance is a concern. In the search for new schistosomicidal drugs, we performed a target-based chemogenomics sc...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Neves, Bruno J., Braga, Rodolpho C., Bezerra, José C. B., Cravo, Pedro V. L., Andrade, Carolina H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287566/
https://ncbi.nlm.nih.gov/pubmed/25569258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003435
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