In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://ncbi.nlm.nih.gov/pubmed/30596650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203340
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