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In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Schistosomiasis is a neglected parasitosis caused by Schistosoma spp. Praziquantel is used for the chemoprophylaxis and treatment of this disease. Although this monotherapy is effective, the risk of resistance and its low efficiency against immature worms compromises its effectiveness. Therefore, it...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Calixto, Nicole Melo, dos Santos, Daniela Braz, Bezerra, José Clecildo Barreto, Silva, Lourival de Almeida
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312253/
https://ncbi.nlm.nih.gov/pubmed/30596650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203340
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