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A Challenging Pie to Splice: Drugging the Spliceosome

Over the last decade, considerable effort has been directed at developing drugs that target the spliceosome. The resulting synthetic and natural product splice modulators have opened new avenues for the interrogation of disease-associated splicing events. In this Minireview, an overview is provided...

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Podrobná bibliografie
Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: León, Brian, Kashyap, Manoj K., Chan, Warren C., Krug, Kelsey A., Castro, Januario E., La Clair, James J., Burkart, Michael D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311392/
https://ncbi.nlm.nih.gov/pubmed/28371109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201701065
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