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Splice Modulation Synergizes Cell Cycle Inhibition
While recognized as a therapeutic target, the spliceosome may offer a robust vector to improve established therapeutics against other protein targets. Here, we describe how modulating the spliceosome using small molecule splice modulators (SPLMs) can prime a cell for sensitivity to a target-specific...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7570451/ https://ncbi.nlm.nih.gov/pubmed/32004428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00833 |
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