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Unconventional Approaches to Modulating the Immunogenicity of Tumor Cells

For several years, it has been known that histone deacetylase inhibitors have the potential to alter the immunogenicity of tumor cells exposed to checkpoint inhibitory immunotherapy antibodies. HDAC inhibitors can rapidly reduce expression of PD-L1 and increase expression of MHCA in various tumor ty...

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Detalhes bibliográficos
Publicado no:Adv Cancer Res
Main Authors: Booth, Laurence, Roberts, Jane L., Kirkwood, John, Poklepovic, Andrew, Dent, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311107/
https://ncbi.nlm.nih.gov/pubmed/29405973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2017.11.004
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