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Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex

Adrenal cortex steroids are essential for body homeostasis, and adrenal insufficiency is a life-threatening condition. Adrenal endocrine activity is maintained through recruitment of subcapsular progenitor cells that follow a unidirectional differentiation path from zona glomerulosa to zona fascicul...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Mathieu, Mickael, Drelon, Coralie, Rodriguez, Stéphanie, Tabbal, Houda, Septier, Amandine, Damon-Soubeyrand, Christelle, Dumontet, Typhanie, Berthon, Annabel, Sahut-Barnola, Isabelle, Djari, Cyril, Batisse-Lignier, Marie, Pointud, Jean-Christophe, Richard, Damien, Kerdivel, Gwenneg, Calméjane, Marie-Ange, Boeva, Valentina, Tauveron, Igor, Lefrançois-Martinez, Anne-Marie, Martinez, Antoine, Val, Pierre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310834/
https://ncbi.nlm.nih.gov/pubmed/30541888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809185115
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