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Inosine, but none of the 8-oxo-purines, is a plausible component of a primordial version of RNA
The emergence of primordial RNA-based life would have required the abiotic synthesis of nucleotides, and their participation in nonenzymatic RNA replication. Although considerable progress has been made toward potentially prebiotic syntheses of the pyrimidine nucleotides (C and U) and their 2-thio v...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310819/ https://ncbi.nlm.nih.gov/pubmed/30509978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814367115 |
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