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RNA-mediated gene fusion in mammalian cells

One of the hallmarks of cancer is the formation of oncogenic fusion genes as a result of chromosomal translocations. Fusion genes are presumed to form before fusion RNA expression. However, studies have reported the presence of fusion RNAs in individuals who were negative for chromosomal translocati...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gupta, Sachin Kumar, Luo, Liming, Yen, Laising
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310785/
https://ncbi.nlm.nih.gov/pubmed/30538195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814704115
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