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RNA-mediated gene fusion in mammalian cells

One of the hallmarks of cancer is the formation of oncogenic fusion genes as a result of chromosomal translocations. Fusion genes are presumed to form before fusion RNA expression. However, studies have reported the presence of fusion RNAs in individuals who were negative for chromosomal translocati...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Gupta, Sachin Kumar, Luo, Liming, Yen, Laising
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310785/
https://ncbi.nlm.nih.gov/pubmed/30538195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814704115
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