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RNA-mediated gene fusion in mammalian cells

One of the hallmarks of cancer is the formation of oncogenic fusion genes as a result of chromosomal translocations. Fusion genes are presumed to form before fusion RNA expression. However, studies have reported the presence of fusion RNAs in individuals who were negative for chromosomal translocati...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gupta, Sachin Kumar, Luo, Liming, Yen, Laising
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310785/
https://ncbi.nlm.nih.gov/pubmed/30538195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814704115
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