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RNA-mediated gene fusion in mammalian cells

One of the hallmarks of cancer is the formation of oncogenic fusion genes as a result of chromosomal translocations. Fusion genes are presumed to form before fusion RNA expression. However, studies have reported the presence of fusion RNAs in individuals who were negative for chromosomal translocati...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Gupta, Sachin Kumar, Luo, Liming, Yen, Laising
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310785/
https://ncbi.nlm.nih.gov/pubmed/30538195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814704115
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