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Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase

Despite the wealth of information available for the reverse transcriptase (RT)-associated ribonuclease H (RNaseH) domain of lentiviruses, gammaretroviruses and long terminal repeat containing retrotransposons, exploiting this information in the form of an RNaseH inhibitor with high specificity and l...

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Detalles Bibliográficos
Publicado en:Future Med Chem
Main Authors: Corona, Angela, Masaoka, Takashi, Tocco, Graziella, Tramontano, Enzo, Le Grice, Stuart FJ
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310216/
https://ncbi.nlm.nih.gov/pubmed/24261890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.178
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