The Orphan Receptor Tie1 Controls Angiogenesis and Vascular Remodeling by Differentially Regulating Tie2 in Tip and Stalk Cells

Tie1 is a mechanistically poorly characterized endothelial cell (EC)-specific orphan receptor. Yet, Tie1 deletion is embryonic lethal and Tie1 has been implicated in critical vascular pathologies, including atherosclerosis and tumor angiogenesis. Here, we show that Tie1 does not function independent...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Rep
मुख्य लेखकों: Savant, Soniya, Porta, Silvia La, Budnik, Annika, Busch, Katrin, Hu, Junhao, Tisch, Nathalie, Korn, Claudia, Valls, Aida Freire, Benest, Andrew V., Terhardt, Dorothee, Qu, Xianghu, Adams, Ralf H., Baldwin, H. Scott, de Almodó var, Carmen Ruiz, Rodewald, Hans-Reimer, Augustin, Hellmut G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309948/
https://ncbi.nlm.nih.gov/pubmed/26344773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.024
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