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Angiopoietin-2 Is Critical for Cytokine-Induced Vascular Leakage
Genetic experiments (loss-of-function and gain-of-function) have established the role of Angiopoietin/Tie ligand/receptor tyrosine kinase system as a regulator of vessel maturation and quiescence. Angiopoietin-2 (Ang-2) acts on Tie2-expressing resting endothelial cells as an antagonistic ligand to n...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734283/ https://ncbi.nlm.nih.gov/pubmed/23940579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070459 |
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