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Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

Akt1 is implicated in cell metabolism, survival migration, and gene expression; however, little is known about the role of specific Akt isoforms during inflammation in vivo. Thus, we directly explored the roles of the isoforms Akt1 and Akt2 in acute inflammation models by using mice deficient in eit...

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Bibliografiske detaljer
Main Authors: Di Lorenzo, Annarita, Fernández-Hernando, Carlos, Cirino, Giuseppe, Sessa, William C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732859/
https://ncbi.nlm.nih.gov/pubmed/19622728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904073106
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