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Akt1 is critical for acute inflammation and histamine-mediated vascular leakage

Akt1 is implicated in cell metabolism, survival migration, and gene expression; however, little is known about the role of specific Akt isoforms during inflammation in vivo. Thus, we directly explored the roles of the isoforms Akt1 and Akt2 in acute inflammation models by using mice deficient in eit...

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Bibliographic Details
Main Authors: Di Lorenzo, Annarita, Fernández-Hernando, Carlos, Cirino, Giuseppe, Sessa, William C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732859/
https://ncbi.nlm.nih.gov/pubmed/19622728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904073106
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