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Tie1: an orphan receptor provides context for angiopoietin-2/Tie2 signaling

Angiopoietin-1/Tie2 (ANG1/Tie2) signaling is well documented as regulating angiogenesis and vessel maturation. This pathway is complicated by involvement of the orphan receptor Tie1, which has been implicated as both a positive and negative regulator of ANG1/Tie2 signaling, and ANG2, which can serve...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mueller, Sarah B., Kontos, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004958/
https://ncbi.nlm.nih.gov/pubmed/27548526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89963
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