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Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells.

BACKGROUND:Fibulin-5 is an extracellular matrix glycoprotein that plays critical roles in vasculogenesis and embryonic development. Deletion of Fibulin-5 in mice results in enhanced skin vascularization and upregulation of the angiogenesis factor angiopoietin-1 (Ang-1), suggesting that Fibulin-5 fun...

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Bibliographic Details
Main Authors: Wilson Chan, Hodan Ismail, Dominique Mayaki, Veronica Sanchez, Kerstin Tiedemann, Elaine C Davis, Sabah N A Hussain
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4909301?pdf=render
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