Phenotypic Characterization of Murine Models of Cerebral Cavernous Malformations

Cerebral cavernous malformations (CCMs) are clusters of dilated capillaries that affect around 0.5% of the population. CCMs exist in two forms, sporadic and familial. Mutations in 3 documented genes, KRIT1 (CCM1), CCM2 and PDCD10 (CCM3), cause the autosomal dominant form of the disease, and somatic...

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Foilsithe in:Lab Invest
Main Authors: Zeineddine, Hussein A., Girard, Romuald, Saadat, Laleh, Shen, Le, Lightle, Rhonda, Moore, Thomas, Cao, Ying, Hobson, Nick, Shenkar, Robert, Avner, Kenneth, Chaudager, Kiranj, Koskimäki, Janne, Polster, Sean P., Fam, Maged D., Shi, Changbin, Lopez-Ramirez, Miguel Alejandro, Tang, Alan T., Gallione, Carol, Kahn, Mark L., Ginsberg, Mark, Marchuk, Douglas A., Awad, Issam A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309944/
https://ncbi.nlm.nih.gov/pubmed/29946133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0030-y
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