A founder mutation in the Ashkenazi Jewish population affecting mRNA splicing of the CCM2 gene is associated with Cerebral Cavernous Malformations: Ashkenazi Jewish founder mutatio...

অনুযায়ী Gallione, Carol J., Solatycki, Ann, Awad, Issam A., Weber, James L., Marchuk, Douglas A.
প্রকাশিত 2011

Loss of p53 Sensitizes Mice with a Mutation in Ccm1 (KRIT1) to Development of Cerebral Vascular Malformations

অনুযায়ী Plummer, Nicholas W., Gallione, Carol J., Srinivasan, Sudha, Zawistowski, Jon S., Louis, David N., Marchuk, Douglas A.
প্রকাশিত 2004

Somatic Mutations in Vascular Malformations of Hereditary Hemorrhagic Telangiectasia Result in Bi-allelic Loss of ENG or ACVRL1

অনুযায়ী Snellings, Daniel A., Gallione, Carol J., Clark, Dewi S., Vozoris, Nicholas T., Faughnan, Marie E., Marchuk, Douglas A.
প্রকাশিত Am J Hum Genet (2019)

Natural Genetic Variation of Integrin Alpha L (Itgal) Modulates Ischemic Brain Injury in Stroke

অনুযায়ী Keum, Sehoon, Lee, Han Kyu, Chu, Pei-Lun, Kan, Matthew J., Huang, Min-Nung, Gallione, Carol J., Gunn, Michael D., Lo, Donald C., Marchuk, Douglas A.
প্রকাশিত 2013

Sturge–Weber Syndrome and Port-Wine Stains Caused by Somatic Mutation in GNAQ

অনুযায়ী Shirley, Matthew D., Tang, Hao, Gallione, Carol J., Baugher, Joseph D., Frelin, Laurence P., Cohen, Bernard, North, Paula E., Marchuk, Douglas A., Comi, Anne M., Pevsner, Jonathan
প্রকাশিত 2013

Lesions from patients with sporadic cerebral cavernous malformations harbor somatic mutations in the CCM genes: evidence for a common biochemical pathway for CCM pathogenesis

অনুযায়ী McDonald, David A., Shi, Changbin, Shenkar, Robert, Gallione, Carol J., Akers, Amy L., Li, Stephanie, De Castro, Nicholas, Berg, Michel J., Corcoran, David L., Awad, Issam A., Marchuk, Douglas A.
প্রকাশিত 2014

A Brain Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease

অনুযায়ী McKerracher, Lisa, Shenkar, Robert, Abbinanti, Matthew, Cao, Ying, Peiper, Amy, Liao, James K., Lightle, Rhonda, Moore, Thomas, Hobson, Nicholas, Gallione, Carol, Ruschel, Joerg, Koskimäki, Janne, Girard, Romuald, Rosen, Kenneth, Marchuk, Douglas, Awad, Issam
প্রকাশিত Transl Stroke Res (2019)

Novel murine models of cerebral cavernous malformations

অনুযায়ী Detter, Matthew R, Shenkar, Robert, Benavides, Christian R, Neilson, Catherine A, Moore, Thomas, Lightle, Rhonda, Hobson, Nicholas, Shen, Le, Cao, Ying, Girard, Romuald, Zhang, Dongdong, Griffin, Erin, Gallione, Carol J, Awad, Issam A, Marchuk, Douglas A
প্রকাশিত Angiogenesis (2020)

Propranolol inhibits cavernous vascular malformations by β1 adrenergic receptor antagonism in animal models

অনুযায়ী Li, Wenqing, Shenkar, Robert, Detter, Mathew R., Moore, Thomas, Benavides, Christian, Lightle, Rhonda, Girard, Romuald, Hobson, Nicholas, Cao, Ying, Li, Yan, Griffin, Erin, Gallione, Carol, Zabramski, Joseph M., Ginsberg, Mark H., Marchuk, Douglas A., Awad, Issam A.
প্রকাশিত J Clin Invest (2021)

B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models

অনুযায়ী Shi, Changbin, Shenkar, Robert, Zeineddine, Hussein A., Girard, Romuald, Fam, Maged D., Austin, Cecilia, Moore, Thomas, Lightle, Rhonda, Zhang, Lingjiao, Wu, Meijing, Cao, Ying, Gunel, Murat, Louvi, Angeliki, Rorrer, Autumn, Gallione, Carol, Marchuk, Douglas A., Awad, Issam A.
প্রকাশিত J Neuroimmune Pharmacol (2016)

RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations

অনুযায়ী Shenkar, Robert, Shi, Changbin, Austin, Cecilia, Moore, Thomas, Lightle, Rhonda, Cao, Ying, Zhang, Lingjiao, Wu, Meijing, Zeineddine, Hussein A., Girard, Romuald, McDonald, David A., Rorrer, Autumn, Gallione, Carol, Pytel, Peter, Liao, James K., Marchuk, Douglas A., Awad, Issam A.
প্রকাশিত Stroke (2016)

Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease

অনুযায়ী Shenkar, Robert, Peiper, Amy, Pardo, Heidy, Moore, Thomas, Lightle, Rhonda, Girard, Romuald, Hobson, Nicholas, Polster, Sean P., Koskimäki, Janne, Zhang, Dongdong, Lyne, Seán B., Cao, Ying, Chaudagar, Kiranj, Saadat, Laleh, Gallione, Carol, Pytel, Peter, Liao, James K., Marchuk, Douglas, Awad, Issam A.
প্রকাশিত Stroke (2019)

EXCEPTIONAL AGGRESSIVENESS OF CEREBRAL CAVERNOUS MALFORMATION DISEASE ASSOCIATED WITH PDCD10 MUTATIONS

অনুযায়ী Shenkar, Robert, Shi, Changbin, Rebeiz, Tania, Stockton, Rebecca A., McDonald, David A., Mikati, Abdul Ghani, Zhang, Lingjiao, Austin, Cecilia, Akers, Amy L., Gallione, Carol J., Rorrer, Autumn, Gunel, Murat, Min, Wang, De Souza, Jorge Marcondes, Lee, Connie, Marchuk, Douglas A., Awad, Issam A.
প্রকাশিত Genet Med (2014)

Micro-Computed Tomography in Murine Models of Cerebral Cavernous Malformations as a Paradigm for Brain Disease

অনুযায়ী Girard, Romuald, Zeineddine, Hussein A., Orsbon, Courtney, Tan, Huan, Moore, Thomas, Hobson, Nick, Shenkar, Robert, Lightle, Rhonda, Shi, Changbin, Fam, Maged D., Cao, Ying, Shen, Le, Neander, April I., Rorrer, Autumn, Gallione, Carol, Tang, Alan T., Kahn, Mark L., Marchuk, Douglas A., Luo, Zhe-Xi, Awad, Issam A.
প্রকাশিত J Neurosci Methods (2016)

Phenotypic Characterization of Murine Models of Cerebral Cavernous Malformations

অনুযায়ী Zeineddine, Hussein A., Girard, Romuald, Saadat, Laleh, Shen, Le, Lightle, Rhonda, Moore, Thomas, Cao, Ying, Hobson, Nick, Shenkar, Robert, Avner, Kenneth, Chaudager, Kiranj, Koskimäki, Janne, Polster, Sean P., Fam, Maged D., Shi, Changbin, Lopez-Ramirez, Miguel Alejandro, Tang, Alan T., Gallione, Carol, Kahn, Mark L., Ginsberg, Mark, Marchuk, Douglas A., Awad, Issam A.
প্রকাশিত Lab Invest (2018)