Micro-Computed Tomography in Murine Models of Cerebral Cavernous Malformations as a Paradigm for Brain Disease

BACKGROUND: Cerebral cavernous malformations (CCMs) are hemorrhagic brain lesions, where murine models allow major mechanistic discoveries, ushering genetic manipulations and preclinical assessment of therapies. Histology for lesion counting and morphometry is essential yet tedious and time consumin...

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Publicado en:J Neurosci Methods
Autores principales: Girard, Romuald, Zeineddine, Hussein A., Orsbon, Courtney, Tan, Huan, Moore, Thomas, Hobson, Nick, Shenkar, Robert, Lightle, Rhonda, Shi, Changbin, Fam, Maged D., Cao, Ying, Shen, Le, Neander, April I., Rorrer, Autumn, Gallione, Carol, Tang, Alan T., Kahn, Mark L., Marchuk, Douglas A., Luo, Zhe-Xi, Awad, Issam A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5003657/
https://ncbi.nlm.nih.gov/pubmed/27345427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2016.06.021
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