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B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models

Cerebral cavernous malformations (CCMs) are relatively common vascular malformations, characterized by increased Rho kinase (ROCK) activity, vascular hyper-permeability and the presence of blood degradation products including non-heme iron. Previous studies revealed robust inflammatory cell infiltra...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Shi, Changbin, Shenkar, Robert, Zeineddine, Hussein A., Girard, Romuald, Fam, Maged D., Austin, Cecilia, Moore, Thomas, Lightle, Rhonda, Zhang, Lingjiao, Wu, Meijing, Cao, Ying, Gunel, Murat, Louvi, Angeliki, Rorrer, Autumn, Gallione, Carol, Marchuk, Douglas A., Awad, Issam A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746226/
https://ncbi.nlm.nih.gov/pubmed/27086141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9670-0
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