B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models

Cerebral cavernous malformations (CCMs) are relatively common vascular malformations, characterized by increased Rho kinase (ROCK) activity, vascular hyper-permeability and the presence of blood degradation products including non-heme iron. Previous studies revealed robust inflammatory cell infiltra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuroimmune Pharmacol
Prif Awduron: Shi, Changbin, Shenkar, Robert, Zeineddine, Hussein A., Girard, Romuald, Fam, Maged D., Austin, Cecilia, Moore, Thomas, Lightle, Rhonda, Zhang, Lingjiao, Wu, Meijing, Cao, Ying, Gunel, Murat, Louvi, Angeliki, Rorrer, Autumn, Gallione, Carol, Marchuk, Douglas A., Awad, Issam A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746226/
https://ncbi.nlm.nih.gov/pubmed/27086141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-016-9670-0
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