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Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80

Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for hematological malignancies (i.e. leukemia and lymphoma), because graft-versus-leukemia (GVL) activity mediated by alloreactive T cells can eliminate residual malignant cells and prevent relapse. However, the same alloreact...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Cassady, Kaniel, Martin, Paul J., Zeng, Defu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308317/
https://ncbi.nlm.nih.gov/pubmed/30622541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03061
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