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Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80
Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for hematological malignancies (i.e. leukemia and lymphoma), because graft-versus-leukemia (GVL) activity mediated by alloreactive T cells can eliminate residual malignant cells and prevent relapse. However, the same alloreact...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6308317/ https://ncbi.nlm.nih.gov/pubmed/30622541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03061 |
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