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B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft versus host disease
Interactions of B7H1 (PD-L1) with its two ligands, PD-1 and CD80, on T cells play a pivotal role in controlling T cell activation, proliferation, anergy, and apoptosis. However, the interactions between the two pathways remain unknown. Using an alloimmune response model of graft-versus-host disease...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4282988/ https://ncbi.nlm.nih.gov/pubmed/25488990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402157 |
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