Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice

Cutaneous sclerosis is one of the most common clinical manifestations of chronic graft-versus-host disease (cGVHD). Donor CD4(+) T and B cells play important roles in cGVHD pathogenesis, but the role of antibodies from donor B cells remains unclear. In the current studies, we generated immunoglobuli...

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Vydáno v:Blood
Hlavní autoři: Jin, Hua, Ni, Xiong, Deng, Ruishu, Song, Qingxiao, Young, James, Cassady, Kaniel, Zhang, Mingfeng, Forman, Stephen, Martin, Paul J., Liu, Qifa, Zeng, Defu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859199/
https://ncbi.nlm.nih.gov/pubmed/26884373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-668145
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