Administration Of Anti-CD20 mAb Is Highly Effective In Preventing But Ineffective In Treating Chronic GVHD While Preserving Strong GVL Effects

Chronic graft-versus-host disease (cGVHD) is an autoimmune-like syndrome, and donor B cells play important roles in augmenting its pathogenesis. B cell-depleting anti-CD20 mAb has been administered before or after cGVHD onset for preventing or treating cGVHD in clinic. Although administration before...

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Detalhes bibliográficos
Main Authors: Johnston, Heather F., Xu, Yajing, Racine, Jeremy J., Cassady, Kaniel, Ni, Xiong, Wu, Tao, Chan, Andrew, Forman, Stephen, Zeng, Defu
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099287/
https://ncbi.nlm.nih.gov/pubmed/24796279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2014.04.028
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