Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1‐autophagy pathway

Melatonin is reportedly associated with intervertebral disc degeneration (IDD). Endplate cartilage is vitally important to intervertebral discs in physiological and pathological conditions. However, the effects and mechanism of melatonin on endplate chondrocytes (EPCs) are still unclear. Herein, we...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Zhang, Zengjie, Lin, Jialiang, Tian, Naifeng, Wu, Yaosen, Zhou, Yifei, Wang, Chenggui, Wang, Qingqing, Jin, Haiming, Chen, Tingting, Nisar, Majid, Zheng, Gang, Xu, Tianzhen, Gao, Weiyang, Zhang, Xiaolei, Wang, Xiangyang
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307776/
https://ncbi.nlm.nih.gov/pubmed/30353656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13903
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