Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1‐autophagy pathway

Melatonin is reportedly associated with intervertebral disc degeneration (IDD). Endplate cartilage is vitally important to intervertebral discs in physiological and pathological conditions. However, the effects and mechanism of melatonin on endplate chondrocytes (EPCs) are still unclear. Herein, we...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Zengjie, Lin, Jialiang, Tian, Naifeng, Wu, Yaosen, Zhou, Yifei, Wang, Chenggui, Wang, Qingqing, Jin, Haiming, Chen, Tingting, Nisar, Majid, Zheng, Gang, Xu, Tianzhen, Gao, Weiyang, Zhang, Xiaolei, Wang, Xiangyang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307776/
https://ncbi.nlm.nih.gov/pubmed/30353656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13903
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