SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis

Mitochondrial dysfunction is an important contributor to the development of osteoarthritis (OA). Sirtuin 3 (SIRT3) regulates diverse mitochondrial proteins to maintain mitochondrial homeostasis, and dihydromyricetin (DHM) is reported as a potential SIRT3 activator. This study aims to explore the rel...

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Bibliografiske detaljer
Udgivet i:Int J Biol Sci
Main Authors: Wang, Jianle, Wang, Ke, Huang, Chongan, Lin, Dongdong, Zhou, Yifei, Wu, Yaosen, Tian, Naifeng, Fan, Pei, Pan, Xiangxiang, Xu, Daoliang, Hu, Jianing, Zhou, Ying, Wang, Xiangyang, Zhang, Xiaolei
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6231225/
https://ncbi.nlm.nih.gov/pubmed/30443190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.27746
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