S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway

In this study, we used murine chondrocytes as an in vitro model and mice exhibiting destabilization of the medial meniscus (DMM) as an in vivo model to investigate the mechanisms through which S-allyl cysteine (SAC) alleviates osteoarthritis (OA). SAC significantly reduced apoptosis and senescence a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Aging (Albany NY)
Main Authors: Shao, Zhenxuan, Pan, Zongyou, Lin, Jialiang, Zhao, Qingqian, Wang, Yuqian, Ni, Libin, Feng, Shiyi, Tian, Naifeng, Wu, Yaosen, Sun, Liaojun, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals 2020
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732291/
https://ncbi.nlm.nih.gov/pubmed/33027770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103757
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