Sinensetin Reduces Osteoarthritis Pathology in the Tert-Butyl Hydroperoxide-Treated Chondrocytes and the Destabilization of the Medial Meniscus Model Mice via the AMPK/mTOR Signaling Pathway

As a common degenerative disease, osteoarthritis (OA) usually causes disability in the elderly and socioeconomic burden. Previous studies have shown that proper autophagy has a protective effect on OA. Sinensetin (Sin) is a methylated flavonoid derived from citrus fruits. Studies have shown that Sin...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Zhou, Wenxian, Shi, Yifeng, Wang, Hui, Yu, Caiyu, Zhu, Huanqing, Wu, Aimin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322586/
https://ncbi.nlm.nih.gov/pubmed/34335275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.713491
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