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Hepatocyte-Derived Lipotoxic Extracellular Vesicle Sphingosine 1-Phosphate Induces Macrophage Chemotaxis

Background: The pathophysiology of non-alcoholic steatohepatitis involves hepatocyte lipotoxicity due to excess saturated free fatty acids and concomitant proinflammatory macrophage effector responses. These include the infiltration of macrophages into hepatic cords in response to incompletely under...

詳細記述

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書誌詳細
出版年:Front Immunol
主要な著者: Liao, Chieh-Yu, Song, Myeong Jun, Gao, Yandong, Mauer, Amy S., Revzin, Alexander, Malhi, Harmeet
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305739/
https://ncbi.nlm.nih.gov/pubmed/30619336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02980
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