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Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis
Nonalcoholic steatohepatitis (NASH) is a lipotoxic disorder, wherein proinflammatory lipids, such as ceramide and its derivative sphingosine 1-phosphate (S1P), contribute to macrophage-associated liver inflammation. For example, we have previously demonstrated a role for S1P in steatotic hepatocyte-...
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| Publicado no: | Am J Physiol Gastrointest Liver Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5401989/ https://ncbi.nlm.nih.gov/pubmed/28039158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00222.2016 |
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