PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway

Gluconeogenesis, generates glucose from small carbohydrate substrates, and drives the metabolic flux in parallel but opposite to glycolysis. The cytoplasmic isoform of phosphoenolpyruvate carboxykinase (PCK1 or PEPCK-C), a rate-limiting enzyme in gluconeogenesis, initiates the gluconeogenesis proces...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Tuo, Lin, Xiang, Jin, Pan, Xuanming, Gao, Qingzhu, Zhang, Guiji, Yang, Yi, Liang, Li, Xia, Jie, Wang, Kai, Tang, Ni
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304441/
https://ncbi.nlm.nih.gov/pubmed/30619751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00611
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