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SLC27A5 deficiency activates NRF2/TXNRD1 pathway by increased lipid peroxidation in HCC
Solute carrier family 27 member 5 (SLC27A5/FATP5) is involved in fatty acid transport and bile acid metabolism; however, little is known about its role in human diseases. Here, we first show that SLC27A5 expression is downregulated in hepatocellular carcinoma (HCC) by DNA hypermethylation, and reduc...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206086/ https://ncbi.nlm.nih.gov/pubmed/31367013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0399-1 |
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