NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

The transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) is a key regulator of the cellular antioxidant response, controlling the expression of genes that counteract oxidative and electrophilic stresses. Many pathological conditions are linked to imbalances in redox homeostasis, i...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Dodson, Matthew, Castro-Portuguez, Raul, Zhang, Donna D.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Implications of lipoxidation in cellular defense and stress pathway
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859567/
https://ncbi.nlm.nih.gov/pubmed/30692038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101107
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