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Ferroptosis: death by lipid peroxidation
Ferroptosis is a regulated form of cell death driven by loss of activity of the lipid repair enzyme glutathione peroxidase 4 (GPX4) and subsequent accumulation of lipid-based reactive oxygen species, particularly lipid hydroperoxides. This form of iron-dependent cell death is genetically, biochemica...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764384/ https://ncbi.nlm.nih.gov/pubmed/26653790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2015.10.014 |
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